WebMyc-tagged overview Overview Co-immunoprecipitation of myc-tagged and HA-tagged proteins in mammalian cells Strong constitutive expression Confirm yeast two-hybrid interactions in mammalian cells Strong clean bands via Western blot More Information Applications Co-immunoprecipitation studies Confirmation of protein-protein interactions WebWestern blot of L363 MM cell and CA46 cells measuring expresison of c-Myc (using ab32072) and GAPDH as the dose of DC-34 increases. c-Myc protein levels are inhibited as a function of the dose of DC-34 in L363 cells; only the highest dose of DC-34 affected c-Myc in the more resistant CA46 Burkitt’s lymphoma cells.
Myc targeted CDK18 promotes ATR and homologous …
Web2 jul. 2024 · Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma. Jian-Fang Ning, Monica Stanciu, Melissa R. … WebLCS-1 is a superoxide dismutase 1 ( SOD1) inhibitor. LCS-1 inhibits SOD1 activity with an IC50 value of 1.07 μM. LCS-1 induces the early- and late-stage apoptosis of multiple myeloma (MM.1S) cells. For research use only. We do not sell to patients. LCS-1 Chemical Structure. CAS No. : 41931-13-9. aru university ranking uk
Cell-to-cell variability in Myc dynamics drives transcriptional ...
WebThe MYC transcription factor regulates a vast number of genes and is implicated in many human malignancies. In some hematological malignancies, MYC is frequently subject to missense mutations that enhance its transformation activity. Here, we use a novel murine cell system to (i) characterize the transcriptional effects of progressively increasing MYC … Web1 feb. 2024 · A GSPT2, GSPT1 and MYC western blot of PSN1 (left panel) or GSPT1 and MYC western blot of HCT116 (right panel) cells treated for 24 h with 0.25 µM, 0.5 µM and 1 µM CC-885 or DMSO vehicle control. Tubulin: loading control. Shown is one representative experiment out of three independent biological replicates. WebShared with My Cloud Home We use cookies and web tracking technologies on this site for various … Shared with My Cloud Home aruunem berry tart